The Science
Dermasync was created with an understanding of the latest peer-reviewed studies that explore the connection between hormones, skin behavior, and the actives that best support each phase of a woman’s cycle.
From this research review, we developed a scientific citations library used by our proprietary routine suggestion engine — a living repository, refined as science evolves.
Estrogen and progesterone don’t just shape mood — they shape sebum, barrier resilience, and inflammation. Our engine is built around the four rhythmic phases a woman’s skin moves through each month.
Our routine suggestions map a well-studied active to the cycle phase where it works best with your skin’s current state.
Cycle timing, self-reported skin state, environmental and lifestyle factors, and your personal history refine your daily routine suggestions. Nothing in our app diagnoses or treats — it educates, informs, suggests, and adapts.
As science evolves, so do we
Dermatology, endocrinology, and cosmetic chemistry are living fields. As new peer-reviewed research emerges, our engine, our suggestions, and the language we use to describe them are reviewed and refined.
You may notice guidance change over time. That’s the point.
Our citations library
43+
peer-reviewed studies referenced
Quarterly
cadence of library review
Most
suggestions come with a citation card
Research on estrogen and progesterone fluctuations traces predictable changes in sebum production, hydration, and inflammatory tone — the pattern our four phases are built around.
Studies on androgen sensitivity, estrogen-mediated collagen support, and progesterone’s role in barrier behavior inform how the engine anticipates what your skin may need next.
The literature on retinoids, niacinamide, azelaic acid, peptides, and gentle exfoliants shapes how we time actives to the phases where they’re most likely to support the skin, not stress it.
From reboot-phase sensitivity to radiance-phase resilience, we lean on research documenting the shifts most women experience — so our language and guidance stay honest and non-diagnostic.
Dermasync is educational and informational — not medical advice or a diagnostic tool. If you’re navigating a specific skin or health concern, we always recommend seeking the advice of a licensed medical professional.
An educational and informational skincare tool that adapts and personalizes skincare routines around a woman’s cycle and personal inputs.
A medical device or healthcare provider. We don’t diagnose or treat — we are not a substitute for a dermatologist or other licensed medical professional.
We make complex science simple with clear, honest language. No absolute claims. No hype. No shame.